Identification, validation and biological characterisation of novel glioblastoma tumour microenvironment subtypes: implications for precision immunotherapy

K White  K Connor, M Meylan, A Bougoüin, M Salvucci, F Bielle, A C O'Farrell, K Sweeney, L Weng, G Bergers, P Dicker, D M Ashley, E S Lipp, J T Low, J Zhao, P Wen, R Prins, M Verreault, A Idbaih, A Biswas, J H M Prehn, D Lambrechts, I Arijs, F Lodi, G Dilcan, M Lamfers, S Leenstra, F Fabro, I Ntafoulis, J M Kros, J Cryan, F Brett, E Quissac, A Beausang, S MacNally, P O'Halloran, J Clerkin, O Bacon, A Kremer, R T Chi Yen, F S Varn, R G W Verhaak, C Sautès-Fridman, W H Fridman, A T Byrne

Ann Oncol. 2023 Mar; 34(3): 300-314.

https://pubmed.ncbi.nlm.nih.gov/36494005/


Low-Intensity Pulsed Ultrasound-Mediated Blood-Brain Barrier Opening Increases Anti-Programmed Death-Ligand 1 Delivery and Efficacy in Gl261 Mouse Model

Mohammed H Ahmed, Isaias Hernández-Verdin, Emie Quissac, Nolwenn Lemaire, Coralie Guerin, Lea Guyonnet, Noël Zahr, Laura Mouton, Mathieu Santin, Alexandra Petiet, Charlotte Schmitt, Guillaume Bouchoux, Michael Canney, Marc Sanson, Maïté Verreault, Alexandre Carpentier, Ahmed Idbaih

Pharmaceutics. 2023 Jan 30;15(2):455

https://pubmed.ncbi.nlm.nih.gov/36839777/


Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma

Maïté Verreault, Irma Segoviano Vilchis, Shai Rosenberg, Nolwenn Lemaire, Charlotte Schmitt, Jérémy Guehennec, Louis Royer-Perron, Jean-Léon Thomas, TuKiet T Lam, Florent Dingli, Damarys Loew, François Ducray, Sophie Paris, Catherine Carpentier, Yannick Marie, Florence Laigle-Donadey, Audrey Rousseau, Natascha Pigat, Florence Boutillon, Franck Bielle, Karima Mokhtari, Stuart J Frank, Aurélien de Reyniès, Khê Hoang-Xuan, Marc Sanson, Vincent Goffin, Ahmed Idbaih

Clin Transl Med. 2022 Jul;12(7):e939

https://pubmed.ncbi.nlm.nih.gov/35808822/


Expression and Prognostic Value of CD80 and CD86 in the Tumor Microenvironment of Newly Diagnosed Glioblastoma

Mohammed H Ahmed, Isaias Hernández-Verdin, Franck Bielle, Maïté Verreault, Julie Lerond, Agusti Alentorn, Marc Sanson, Ahmed Idbaih

Can J Neurol Sci. 2023 Mar;50(2):234-242

https://pubmed.ncbi.nlm.nih.gov/35022089/


Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in glioblastoma

Federica Fabro, Nynke M Kannegieter, Erik L de Graaf, Karla Queiroz, Martine L M Lamfers, Anna Ressa, Sieger Leenstra

Front Oncol. 2022 Nov 3;12:1012236

https://pubmed.ncbi.nlm.nih.gov/36408180/


An autologous ex vivo model for exploring patient-specific responses to viro-immunotherapy in glioblastoma

Eftychia Stavrakaki, Wouter B.L. van den Bossche, Lisette B. Vogelezang, Cristina Teodosio, Dana M. Mustafa, Jacques J.M. van Dongen, Clemens M.F. Dirven, Rutger K. Balvers, and Martine L. Lamfers

Cell Rep Methods. 2024 Mar 25;4(3):100716.

https://pubmed.ncbi.nlm.nih.gov/38430913/